Applying positivity constraints to q-space trajectory imaging: The QTI+ implementation

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  • Deneb Boito
  • Magnus Herberthson
  • Tom Dela Haije
  • Evren Özarslan

Diffusion MRI is a powerful technique sensitive to the microstructure of heterogeneous media. By relating the dMRI signal obtained via general gradient waveforms to the moments of an underlying diffusion tensor distribution, q-space trajectory imaging (QTI) provides several quantities indicative of the structural composition of the medium. Substantial improvements in the reliability of the produced estimates has been achieved via incorporating necessary positivity constraints in the estimation by employing Semidefinite Programming. Here we present the Matlab code implementing said constraints, provide a simple example showing the main functionalities of the package, and point to resources within the package that can be used to reproduce results recently published with this software. The block-based structure of our implementation allows the selection of steps to be performed, and facilitates the incorporation of new constraints in future releases.

OriginalsprogEngelsk
Artikelnummer101030
TidsskriftSoftwareX
Vol/bind18
Antal sider6
ISSN2352-7110
DOI
StatusUdgivet - jun. 2022

Bibliografisk note

Funding Information:
This Project was financially supported by Link?ping University Center for Industrial Information Technology (CENIIT), Sweden, LiU Cancer, VINNOVA/ITEA3 17021 IMPACT, Analytic Imaging Diagnostic Arena (AIDA), and the Swedish Foundation for Strategic Research (RMX18-0056). Tom Dela Haije was supported by a research grant (00028384) from VILLUM FONDEN, Denmark.

Funding Information:
This Project was financially supported by Linköping University Center for Industrial Information Technology (CENIIT), Sweden , LiU Cancer, VINNOVA/ITEA3 17021 IMPACT, Analytic Imaging Diagnostic Arena (AIDA), and the Swedish Foundation for Strategic Research ( RMX18-0056 ). Tom Dela Haije was supported by a research grant ( 00028384 ) from VILLUM FONDEN, Denmark .

Publisher Copyright:
© 2022 The Authors

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