Ansatte – Københavns Universitet

Automatic correction of dental artifacts in PET/MRI

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Claes N. Ladefoged, Flemming L. Andersen, Sune Keller, Thomas Beyer, Ian Law, Liselotte Højgaard, Sune Darkner, Francois Bernard Lauze

A challenge when using current magnetic resonance (MR)-based attenuation correction in positron emission tomography/MR imaging (PET/MRI) is that the MRIs can have a signal void around the dental fillings that is segmented as artificial air-regions in the attenuation map. For artifacts connected to the background, we propose an extension to an existing active contour algorithm to delineate the outer contour using the non-attenuation corrected PET image and the original attenuation map. We propose a combination of two different methods for differentiating the artifacts within the body from the anatomical air-regions by first using a template of artifact regions, and second, representing the artifact regions with a combination of active shape models and k-nearest-neighbors. The accuracy of the combined method has been evaluated using 25 18 F-fluorodeoxyglucose PET/MR patients. Results showed that the approach was able to correct an average of 97+/- 3% of the artifact areas.
TidsskriftSPIE Journal of Medical Imaging
Antal sider13
StatusUdgivet - 2015

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