Quantitative analysis of airway abnormalities in CT

Publikation: Bidrag til bog/antologi/rapportKonferencebidrag i proceedingsForskningfagfællebedømt

Standard

Quantitative analysis of airway abnormalities in CT. / Petersen, Jens; Lo, Pechin Chien Pau; Nielsen, Mads; Edula, Goutham; Ashraf, Haseem; Dirksen, Asger; de Bruijne, Marleen.

Medical Imaging 2010: computer-aided Diagnosis. red. / Nico Karssemeijer; Ronald M. Summers. SPIE - International Society for Optical Engineering, 2010. 76241S (Progress in Biomedical Optics and Imaging; Nr. 34, Bind 11).

Publikation: Bidrag til bog/antologi/rapportKonferencebidrag i proceedingsForskningfagfællebedømt

Harvard

Petersen, J, Lo, PCP, Nielsen, M, Edula, G, Ashraf, H, Dirksen, A & de Bruijne, M 2010, Quantitative analysis of airway abnormalities in CT. i N Karssemeijer & RM Summers (red), Medical Imaging 2010: computer-aided Diagnosis., 76241S, SPIE - International Society for Optical Engineering, Progress in Biomedical Optics and Imaging, nr. 34, bind 11, Medical Imaging 2010, San Diego, USA, 16/02/2010. https://doi.org/10.1117/12.843937

APA

Petersen, J., Lo, P. C. P., Nielsen, M., Edula, G., Ashraf, H., Dirksen, A., & de Bruijne, M. (2010). Quantitative analysis of airway abnormalities in CT. I N. Karssemeijer, & R. M. Summers (red.), Medical Imaging 2010: computer-aided Diagnosis [76241S] SPIE - International Society for Optical Engineering. Progress in Biomedical Optics and Imaging, Nr. 34, Bind. 11 https://doi.org/10.1117/12.843937

Vancouver

Petersen J, Lo PCP, Nielsen M, Edula G, Ashraf H, Dirksen A o.a. Quantitative analysis of airway abnormalities in CT. I Karssemeijer N, Summers RM, red., Medical Imaging 2010: computer-aided Diagnosis. SPIE - International Society for Optical Engineering. 2010. 76241S. (Progress in Biomedical Optics and Imaging; Nr. 34, Bind 11). https://doi.org/10.1117/12.843937

Author

Petersen, Jens ; Lo, Pechin Chien Pau ; Nielsen, Mads ; Edula, Goutham ; Ashraf, Haseem ; Dirksen, Asger ; de Bruijne, Marleen. / Quantitative analysis of airway abnormalities in CT. Medical Imaging 2010: computer-aided Diagnosis. red. / Nico Karssemeijer ; Ronald M. Summers. SPIE - International Society for Optical Engineering, 2010. (Progress in Biomedical Optics and Imaging; Nr. 34, Bind 11).

Bibtex

@inproceedings{434865f0cd6611dea1f3000ea68e967b,
title = "Quantitative analysis of airway abnormalities in CT",
abstract = "A coupled surface graph cut algorithm for airway wall segmentation from Computed Tomography (CT) images is presented. Using cost functions that highlight both inner and outer wall borders, the method combines the search for both borders into one graph cut. The proposed method is evaluated on 173 manually segmented images extracted from 15 different subjects and shown to give accurate results, with 37{\%} less errors than the Full Width at Half Maximum (FWHM) algorithm and 62{\%} less than a similar graph cut method without coupled surfaces. Common measures of airway wall thickness such as the Interior Area (IA) and Wall Area percentage (WA{\%}) was measured by the proposed method on a total of 723 CT scans from a lung cancer screening study. These measures were significantly different for participants with Chronic Obstructive Pulmonary Disease (COPD) compared to asymptomatic participants. Furthermore, reproducibility was good as confirmed by repeat scans and the measures correlated well with the outcomes of pulmonary function tests, demonstrating the use of the algorithm as a COPD diagnostic tool. Additionally, a new measure of airway wall thickness is proposed, Normalized Wall Intensity Sum (NWIS). NWIS is shown to correlate better with lung function test values and to be more reproducible than previous measures IA, WA{\%} and airway wall thickness at a lumen perimeter of 10 mm (PI10).",
author = "Jens Petersen and Lo, {Pechin Chien Pau} and Mads Nielsen and Goutham Edula and Haseem Ashraf and Asger Dirksen and {de Bruijne}, Marleen",
year = "2010",
doi = "10.1117/12.843937",
language = "English",
series = "Progress in Biomedical Optics and Imaging",
publisher = "SPIE - International Society for Optical Engineering",
number = "34",
editor = "Nico Karssemeijer and Summers, {Ronald M.}",
booktitle = "Medical Imaging 2010",
note = "Medical Imaging 2010 : computer-aided diagnosis ; Conference date: 16-02-2010 Through 18-02-2010",

}

RIS

TY - GEN

T1 - Quantitative analysis of airway abnormalities in CT

AU - Petersen, Jens

AU - Lo, Pechin Chien Pau

AU - Nielsen, Mads

AU - Edula, Goutham

AU - Ashraf, Haseem

AU - Dirksen, Asger

AU - de Bruijne, Marleen

PY - 2010

Y1 - 2010

N2 - A coupled surface graph cut algorithm for airway wall segmentation from Computed Tomography (CT) images is presented. Using cost functions that highlight both inner and outer wall borders, the method combines the search for both borders into one graph cut. The proposed method is evaluated on 173 manually segmented images extracted from 15 different subjects and shown to give accurate results, with 37% less errors than the Full Width at Half Maximum (FWHM) algorithm and 62% less than a similar graph cut method without coupled surfaces. Common measures of airway wall thickness such as the Interior Area (IA) and Wall Area percentage (WA%) was measured by the proposed method on a total of 723 CT scans from a lung cancer screening study. These measures were significantly different for participants with Chronic Obstructive Pulmonary Disease (COPD) compared to asymptomatic participants. Furthermore, reproducibility was good as confirmed by repeat scans and the measures correlated well with the outcomes of pulmonary function tests, demonstrating the use of the algorithm as a COPD diagnostic tool. Additionally, a new measure of airway wall thickness is proposed, Normalized Wall Intensity Sum (NWIS). NWIS is shown to correlate better with lung function test values and to be more reproducible than previous measures IA, WA% and airway wall thickness at a lumen perimeter of 10 mm (PI10).

AB - A coupled surface graph cut algorithm for airway wall segmentation from Computed Tomography (CT) images is presented. Using cost functions that highlight both inner and outer wall borders, the method combines the search for both borders into one graph cut. The proposed method is evaluated on 173 manually segmented images extracted from 15 different subjects and shown to give accurate results, with 37% less errors than the Full Width at Half Maximum (FWHM) algorithm and 62% less than a similar graph cut method without coupled surfaces. Common measures of airway wall thickness such as the Interior Area (IA) and Wall Area percentage (WA%) was measured by the proposed method on a total of 723 CT scans from a lung cancer screening study. These measures were significantly different for participants with Chronic Obstructive Pulmonary Disease (COPD) compared to asymptomatic participants. Furthermore, reproducibility was good as confirmed by repeat scans and the measures correlated well with the outcomes of pulmonary function tests, demonstrating the use of the algorithm as a COPD diagnostic tool. Additionally, a new measure of airway wall thickness is proposed, Normalized Wall Intensity Sum (NWIS). NWIS is shown to correlate better with lung function test values and to be more reproducible than previous measures IA, WA% and airway wall thickness at a lumen perimeter of 10 mm (PI10).

U2 - 10.1117/12.843937

DO - 10.1117/12.843937

M3 - Article in proceedings

T3 - Progress in Biomedical Optics and Imaging

BT - Medical Imaging 2010

A2 - Karssemeijer, Nico

A2 - Summers, Ronald M.

PB - SPIE - International Society for Optical Engineering

T2 - Medical Imaging 2010

Y2 - 16 February 2010 through 18 February 2010

ER -

ID: 15685924