Reorganization of Sound Location Processing in the Auditory Cortex of Blind Humans

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Standard

Reorganization of Sound Location Processing in the Auditory Cortex of Blind Humans. / Van Der Heijden, Kiki; Formisano, Elia; Valente, Giancarlo; Zhan, Minye; Kupers, Ron; De Gelder, Beatrice.

I: Cerebral Cortex, Bind 30, Nr. 3, 2020, s. 1103-1116.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Van Der Heijden, K, Formisano, E, Valente, G, Zhan, M, Kupers, R & De Gelder, B 2020, 'Reorganization of Sound Location Processing in the Auditory Cortex of Blind Humans', Cerebral Cortex, bind 30, nr. 3, s. 1103-1116. https://doi.org/10.1093/cercor/bhz151

APA

Van Der Heijden, K., Formisano, E., Valente, G., Zhan, M., Kupers, R., & De Gelder, B. (2020). Reorganization of Sound Location Processing in the Auditory Cortex of Blind Humans. Cerebral Cortex, 30(3), 1103-1116. https://doi.org/10.1093/cercor/bhz151

Vancouver

Van Der Heijden K, Formisano E, Valente G, Zhan M, Kupers R, De Gelder B. Reorganization of Sound Location Processing in the Auditory Cortex of Blind Humans. Cerebral Cortex. 2020;30(3):1103-1116. https://doi.org/10.1093/cercor/bhz151

Author

Van Der Heijden, Kiki ; Formisano, Elia ; Valente, Giancarlo ; Zhan, Minye ; Kupers, Ron ; De Gelder, Beatrice. / Reorganization of Sound Location Processing in the Auditory Cortex of Blind Humans. I: Cerebral Cortex. 2020 ; Bind 30, Nr. 3. s. 1103-1116.

Bibtex

@article{8524260befde4f058766cb83eb602274,
title = "Reorganization of Sound Location Processing in the Auditory Cortex of Blind Humans",
abstract = "Auditory spatial tasks induce functional activation in the occipital - visual - cortex of early blind humans. Less is known about the effects of blindness on auditory spatial processing in the temporal - auditory - cortex. Here, we investigated spatial (azimuth) processing in congenitally and early blind humans with a phase-encoding functional magnetic resonance imaging (fMRI) paradigm. Our results show that functional activation in response to sounds in general - independent of sound location - was stronger in the occipital cortex but reduced in the medial temporal cortex of blind participants in comparison with sighted participants. Additionally, activation patterns for binaural spatial processing were different for sighted and blind participants in planum temporale. Finally, fMRI responses in the auditory cortex of blind individuals carried less information on sound azimuth position than those in sighted individuals, as assessed with a 2-channel, opponent coding model for the cortical representation of sound azimuth. These results indicate that early visual deprivation results in reorganization of binaural spatial processing in the auditory cortex and that blind individuals may rely on alternative mechanisms for processing azimuth position.",
keywords = "auditory cortex, blindness, cortical plasticity, functional magnetic resonance imaging, sound localization",
author = "{Van Der Heijden}, Kiki and Elia Formisano and Giancarlo Valente and Minye Zhan and Ron Kupers and {De Gelder}, Beatrice",
year = "2020",
doi = "10.1093/cercor/bhz151",
language = "English",
volume = "30",
pages = "1103--1116",
journal = "Cerebral Cortex",
issn = "1047-3211",
publisher = "Oxford University Press",
number = "3",

}

RIS

TY - JOUR

T1 - Reorganization of Sound Location Processing in the Auditory Cortex of Blind Humans

AU - Van Der Heijden, Kiki

AU - Formisano, Elia

AU - Valente, Giancarlo

AU - Zhan, Minye

AU - Kupers, Ron

AU - De Gelder, Beatrice

PY - 2020

Y1 - 2020

N2 - Auditory spatial tasks induce functional activation in the occipital - visual - cortex of early blind humans. Less is known about the effects of blindness on auditory spatial processing in the temporal - auditory - cortex. Here, we investigated spatial (azimuth) processing in congenitally and early blind humans with a phase-encoding functional magnetic resonance imaging (fMRI) paradigm. Our results show that functional activation in response to sounds in general - independent of sound location - was stronger in the occipital cortex but reduced in the medial temporal cortex of blind participants in comparison with sighted participants. Additionally, activation patterns for binaural spatial processing were different for sighted and blind participants in planum temporale. Finally, fMRI responses in the auditory cortex of blind individuals carried less information on sound azimuth position than those in sighted individuals, as assessed with a 2-channel, opponent coding model for the cortical representation of sound azimuth. These results indicate that early visual deprivation results in reorganization of binaural spatial processing in the auditory cortex and that blind individuals may rely on alternative mechanisms for processing azimuth position.

AB - Auditory spatial tasks induce functional activation in the occipital - visual - cortex of early blind humans. Less is known about the effects of blindness on auditory spatial processing in the temporal - auditory - cortex. Here, we investigated spatial (azimuth) processing in congenitally and early blind humans with a phase-encoding functional magnetic resonance imaging (fMRI) paradigm. Our results show that functional activation in response to sounds in general - independent of sound location - was stronger in the occipital cortex but reduced in the medial temporal cortex of blind participants in comparison with sighted participants. Additionally, activation patterns for binaural spatial processing were different for sighted and blind participants in planum temporale. Finally, fMRI responses in the auditory cortex of blind individuals carried less information on sound azimuth position than those in sighted individuals, as assessed with a 2-channel, opponent coding model for the cortical representation of sound azimuth. These results indicate that early visual deprivation results in reorganization of binaural spatial processing in the auditory cortex and that blind individuals may rely on alternative mechanisms for processing azimuth position.

KW - auditory cortex

KW - blindness

KW - cortical plasticity

KW - functional magnetic resonance imaging

KW - sound localization

U2 - 10.1093/cercor/bhz151

DO - 10.1093/cercor/bhz151

M3 - Journal article

C2 - 31504283

AN - SCOPUS:85083042199

VL - 30

SP - 1103

EP - 1116

JO - Cerebral Cortex

JF - Cerebral Cortex

SN - 1047-3211

IS - 3

ER -

ID: 242707483