Clinical and parasitological studies on malaria in Liberian adults living under intense malaria transmission
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Clinical and parasitological studies on malaria in Liberian adults living under intense malaria transmission. / Petersen, E; Hogh, B; Marbiah, N T; Dolopaie, E; Gottschau, A; Hanson, A P; Bjorkman, A.
In: Annals of Tropical Medicine and Parasitology, Vol. 85, No. 6, 12.1991, p. 577-84.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Clinical and parasitological studies on malaria in Liberian adults living under intense malaria transmission
AU - Petersen, E
AU - Hogh, B
AU - Marbiah, N T
AU - Dolopaie, E
AU - Gottschau, A
AU - Hanson, A P
AU - Bjorkman, A
PY - 1991/12
Y1 - 1991/12
N2 - Occurrence of fevers and chills, headaches and body and joint pains, and body temperature and malaria parasitaemias were recorded monthly for a year for 121 Liberian adults. There was no apparent correlation between any of the symptoms and the presence or density of blood parasites; it was therefore not possible to define a case of clinical malaria in the study population, which was probably highly immune to infection. Only a few people with patent blood infections had elevated blood temperatures and these were below 37.5 degrees C. Malaria prevalence and levels of parasitaemia declined with age and indicated that immunity continues to develop well into adult age. The data did not support the view that adults experience symptoms at lower parasitaemias than children. Pregnant and non-pregnant women had similar levels of symptoms, but high levels of parasitaemia were found more frequently in the pregnant group.
AB - Occurrence of fevers and chills, headaches and body and joint pains, and body temperature and malaria parasitaemias were recorded monthly for a year for 121 Liberian adults. There was no apparent correlation between any of the symptoms and the presence or density of blood parasites; it was therefore not possible to define a case of clinical malaria in the study population, which was probably highly immune to infection. Only a few people with patent blood infections had elevated blood temperatures and these were below 37.5 degrees C. Malaria prevalence and levels of parasitaemia declined with age and indicated that immunity continues to develop well into adult age. The data did not support the view that adults experience symptoms at lower parasitaemias than children. Pregnant and non-pregnant women had similar levels of symptoms, but high levels of parasitaemia were found more frequently in the pregnant group.
KW - Adult
KW - Age Factors
KW - Body Temperature
KW - Female
KW - Fever/parasitology
KW - Follow-Up Studies
KW - Headache/parasitology
KW - Humans
KW - Liberia
KW - Malaria/blood
KW - Male
KW - Prospective Studies
KW - Seasons
KW - Sex Factors
M3 - Journal article
C2 - 1811434
VL - 85
SP - 577
EP - 584
JO - Pathogens and Global Health
JF - Pathogens and Global Health
SN - 2047-7724
IS - 6
ER -
ID: 203012112