Controlled trial of lambda-cyhalothrin impregnated bed nets and Maloprim chemosuppression to control malaria in children living in a holoendemic area of Sierra Leone, west Africa. Study design and preliminary results
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Controlled trial of lambda-cyhalothrin impregnated bed nets and Maloprim chemosuppression to control malaria in children living in a holoendemic area of Sierra Leone, west Africa. Study design and preliminary results. / Petersen, E; Marbiah, N T; Magbiti, E; Lines, J D; Maude, G H; Høgh, B; Curtis, C; Greenwood, B; Bradley, D.
In: Parassitologia, Vol. 35 Suppl, 07.1993, p. 81-5.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Controlled trial of lambda-cyhalothrin impregnated bed nets and Maloprim chemosuppression to control malaria in children living in a holoendemic area of Sierra Leone, west Africa. Study design and preliminary results
AU - Petersen, E
AU - Marbiah, N T
AU - Magbiti, E
AU - Lines, J D
AU - Maude, G H
AU - Høgh, B
AU - Curtis, C
AU - Greenwood, B
AU - Bradley, D
PY - 1993/7
Y1 - 1993/7
N2 - The effect of lambda-cyhalothrin impregnated bed nets and maloprim/placebo was studied in approximately 1,500 children living in 17 villages in a rural area of Sierra Leone, approximately 150 miles south east of Freetown, 30 miles north of the town of Bo. Villages were selected randomly amongst villages with impregnated bed nets and villages with no nets at all. Within these villages, children with ages ranging between 3 months to 6 years were chosen to receive maloprim or a double-blind distributed placebo fortnightly. In the villages randomised to receive nets, all beds have received nets. Malaria morbidity is estimated from weekly active case detection, and the impact on the Anopheles vector is being estimated by indoor spray catching, exit trap catching, human night landing catches and light trap catches. During the first 8 weeks of the intervention there was a significant reduction in slide positive rates, reported fever rates and children with temperature > or = 37.5 degrees C in the villages with impregnated bed nets.
AB - The effect of lambda-cyhalothrin impregnated bed nets and maloprim/placebo was studied in approximately 1,500 children living in 17 villages in a rural area of Sierra Leone, approximately 150 miles south east of Freetown, 30 miles north of the town of Bo. Villages were selected randomly amongst villages with impregnated bed nets and villages with no nets at all. Within these villages, children with ages ranging between 3 months to 6 years were chosen to receive maloprim or a double-blind distributed placebo fortnightly. In the villages randomised to receive nets, all beds have received nets. Malaria morbidity is estimated from weekly active case detection, and the impact on the Anopheles vector is being estimated by indoor spray catching, exit trap catching, human night landing catches and light trap catches. During the first 8 weeks of the intervention there was a significant reduction in slide positive rates, reported fever rates and children with temperature > or = 37.5 degrees C in the villages with impregnated bed nets.
KW - Animals
KW - Anopheles
KW - Bedding and Linens/economics
KW - Child
KW - Child, Preschool
KW - Dapsone/economics
KW - Double-Blind Method
KW - Drug Combinations
KW - Fever/epidemiology
KW - Humans
KW - Infant
KW - Insect Vectors
KW - Malaria/economics
KW - Mosquito Control/economics
KW - Nitriles
KW - Plasmodium
KW - Pyrethrins
KW - Pyrimethamine/economics
KW - Sierra Leone/epidemiology
M3 - Journal article
C2 - 8233620
VL - 35 Suppl
SP - 81
EP - 85
JO - Parassitologia
JF - Parassitologia
SN - 0048-2951
ER -
ID: 203012398