Boron nanoparticles inhibit turnour growth by boron neutron capture therapy in the murine B16-OVA model

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Standard

Boron nanoparticles inhibit turnour growth by boron neutron capture therapy in the murine B16-OVA model. / Petersen, Mikkel Steen; Petersen, Charlotte Christie; Agger, Ralf; Sutmutter, Marjolein; Jensen, Martin Roland; Sørensen, Palle G.; Mortensen, Michael Wrang; Hansen, Thomas; Bjørnholm, Thomas; Gundersen, Hans Jørgen; Huiskamp, Rene; Hokland, Marianne.

I: Anticancer Research, Bind 28, 2008, s. 571-576.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Petersen, MS, Petersen, CC, Agger, R, Sutmutter, M, Jensen, MR, Sørensen, PG, Mortensen, MW, Hansen, T, Bjørnholm, T, Gundersen, HJ, Huiskamp, R & Hokland, M 2008, 'Boron nanoparticles inhibit turnour growth by boron neutron capture therapy in the murine B16-OVA model', Anticancer Research, bind 28, s. 571-576.

APA

Petersen, M. S., Petersen, C. C., Agger, R., Sutmutter, M., Jensen, M. R., Sørensen, P. G., Mortensen, M. W., Hansen, T., Bjørnholm, T., Gundersen, H. J., Huiskamp, R., & Hokland, M. (2008). Boron nanoparticles inhibit turnour growth by boron neutron capture therapy in the murine B16-OVA model. Anticancer Research, 28, 571-576.

Vancouver

Petersen MS, Petersen CC, Agger R, Sutmutter M, Jensen MR, Sørensen PG o.a. Boron nanoparticles inhibit turnour growth by boron neutron capture therapy in the murine B16-OVA model. Anticancer Research. 2008;28:571-576.

Author

Petersen, Mikkel Steen ; Petersen, Charlotte Christie ; Agger, Ralf ; Sutmutter, Marjolein ; Jensen, Martin Roland ; Sørensen, Palle G. ; Mortensen, Michael Wrang ; Hansen, Thomas ; Bjørnholm, Thomas ; Gundersen, Hans Jørgen ; Huiskamp, Rene ; Hokland, Marianne. / Boron nanoparticles inhibit turnour growth by boron neutron capture therapy in the murine B16-OVA model. I: Anticancer Research. 2008 ; Bind 28. s. 571-576.

Bibtex

@article{8008dfd07fe011dd81b0000ea68e967b,
title = "Boron nanoparticles inhibit turnour growth by boron neutron capture therapy in the murine B16-OVA model",
abstract = "Background: Boron neutron capture therapy usually relies on soluble, rather than particulate, boron compounds. This study evaluated the use of a novel boron nanoparticle for boron neutron capture therapy. Materials and Methods: Two hundred and fifty thousand B16-OVA tumour cells, pre-incubated with boron nanoparticles for 12 hours, were injected subcutaneously into C57BL16J mice. The tumour sites were exposed to different doses of neutron radiation one, four, or eight days after tumour cell inoculation. Results: When the tumour site was irradiated with thermal neutrons one day after injection, tumour growth was delayed and the treated mice survived longer than untreated controls (median survival time 20 days (N=8) compared with 10 days (N=7) for untreated mice). Conclusion: Boron nanoparticles significantly delay the growth of an aggressive B16-OVA tumour in vivo by boron neutron capture therapy.",
keywords = "Faculty of Science",
author = "Petersen, {Mikkel Steen} and Petersen, {Charlotte Christie} and Ralf Agger and Marjolein Sutmutter and Jensen, {Martin Roland} and S{\o}rensen, {Palle G.} and Mortensen, {Michael Wrang} and Thomas Hansen and Thomas Bj{\o}rnholm and Gundersen, {Hans J{\o}rgen} and Rene Huiskamp and Marianne Hokland",
year = "2008",
language = "English",
volume = "28",
pages = "571--576",
journal = "Anticancer Research",
issn = "0250-7005",
publisher = "International Institute of Anticancer Research",

}

RIS

TY - JOUR

T1 - Boron nanoparticles inhibit turnour growth by boron neutron capture therapy in the murine B16-OVA model

AU - Petersen, Mikkel Steen

AU - Petersen, Charlotte Christie

AU - Agger, Ralf

AU - Sutmutter, Marjolein

AU - Jensen, Martin Roland

AU - Sørensen, Palle G.

AU - Mortensen, Michael Wrang

AU - Hansen, Thomas

AU - Bjørnholm, Thomas

AU - Gundersen, Hans Jørgen

AU - Huiskamp, Rene

AU - Hokland, Marianne

PY - 2008

Y1 - 2008

N2 - Background: Boron neutron capture therapy usually relies on soluble, rather than particulate, boron compounds. This study evaluated the use of a novel boron nanoparticle for boron neutron capture therapy. Materials and Methods: Two hundred and fifty thousand B16-OVA tumour cells, pre-incubated with boron nanoparticles for 12 hours, were injected subcutaneously into C57BL16J mice. The tumour sites were exposed to different doses of neutron radiation one, four, or eight days after tumour cell inoculation. Results: When the tumour site was irradiated with thermal neutrons one day after injection, tumour growth was delayed and the treated mice survived longer than untreated controls (median survival time 20 days (N=8) compared with 10 days (N=7) for untreated mice). Conclusion: Boron nanoparticles significantly delay the growth of an aggressive B16-OVA tumour in vivo by boron neutron capture therapy.

AB - Background: Boron neutron capture therapy usually relies on soluble, rather than particulate, boron compounds. This study evaluated the use of a novel boron nanoparticle for boron neutron capture therapy. Materials and Methods: Two hundred and fifty thousand B16-OVA tumour cells, pre-incubated with boron nanoparticles for 12 hours, were injected subcutaneously into C57BL16J mice. The tumour sites were exposed to different doses of neutron radiation one, four, or eight days after tumour cell inoculation. Results: When the tumour site was irradiated with thermal neutrons one day after injection, tumour growth was delayed and the treated mice survived longer than untreated controls (median survival time 20 days (N=8) compared with 10 days (N=7) for untreated mice). Conclusion: Boron nanoparticles significantly delay the growth of an aggressive B16-OVA tumour in vivo by boron neutron capture therapy.

KW - Faculty of Science

M3 - Journal article

VL - 28

SP - 571

EP - 576

JO - Anticancer Research

JF - Anticancer Research

SN - 0250-7005

ER -

ID: 5996759