TY - GEN

T1 - Effect of projective viewpoint in detecting temporal density changes

AU - Raundahl, Jakob

AU - Nielsen, Mads

AU - Olsen, Ole Fogh

AU - Bagger, Yu Z.

PY - 2004

Y1 - 2004

N2 - An important question in mammographic image analysis is the importance of the projected view of the breast. Can temporal changes in density be detected equally well using either one of the commonly available views Medio-Lateral (ML) and Cranio-Caudal (CC) or a combination of the two? Two sets of mammograms of 50 patients in a double-blind, placebo controlled hormone replacement therapy (HRT) experiment were used. One set of ML and CC view from 1999 and one from 2001. HRT increases density which means that the degree ofseparation of the populations (one group receiving HRT and the other placebo) can be used as a measure of how much density change information is carried in a particular view or combination of views. Earlier results have shown a high correlation between CC and ML views leading to the conclusion that only one of them is needed for density assessment purposes. A similar high correlation coefficient was observed in this study (0.85), while the correlation between changes was a bit lower (0.71). Using both views to separate the patients receiving hormones from the ones receiving placebo increased the area under corresponding ROC curves from 0.76 ± 0.04 to 0.79 ± 0.04.

AB - An important question in mammographic image analysis is the importance of the projected view of the breast. Can temporal changes in density be detected equally well using either one of the commonly available views Medio-Lateral (ML) and Cranio-Caudal (CC) or a combination of the two? Two sets of mammograms of 50 patients in a double-blind, placebo controlled hormone replacement therapy (HRT) experiment were used. One set of ML and CC view from 1999 and one from 2001. HRT increases density which means that the degree ofseparation of the populations (one group receiving HRT and the other placebo) can be used as a measure of how much density change information is carried in a particular view or combination of views. Earlier results have shown a high correlation between CC and ML views leading to the conclusion that only one of them is needed for density assessment purposes. A similar high correlation coefficient was observed in this study (0.85), while the correlation between changes was a bit lower (0.71). Using both views to separate the patients receiving hormones from the ones receiving placebo increased the area under corresponding ROC curves from 0.76 ± 0.04 to 0.79 ± 0.04.

U2 - 10.1117/12.535319

DO - 10.1117/12.535319

M3 - Article in proceedings

T3 - Medical Imaging 2004: Image Processing

SP - 85

EP - 92

BT - Proceedings of SPIE

Y2 - 29 November 2010

ER -