Impact of device programming on the success of the first anti-tachycardia pacing therapy: An anonymized large-scale study

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Impact of device programming on the success of the first anti-tachycardia pacing therapy : An anonymized large-scale study. / Shakibfar, Saeed; Krause, Oswin; Lund-Andersen, Casper; Strycko, Filip; Moll, Jonas; Osman Andersen, Tariq; Høgh Petersen, Helen; Hastrup Svendsen, Jesper; Igel, Christian.

I: PLoS ONE, Bind 14, Nr. 8, e0219533, 2019.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Shakibfar, S, Krause, O, Lund-Andersen, C, Strycko, F, Moll, J, Osman Andersen, T, Høgh Petersen, H, Hastrup Svendsen, J & Igel, C 2019, 'Impact of device programming on the success of the first anti-tachycardia pacing therapy: An anonymized large-scale study', PLoS ONE, bind 14, nr. 8, e0219533. https://doi.org/10.1371/journal.pone.0219533

APA

Shakibfar, S., Krause, O., Lund-Andersen, C., Strycko, F., Moll, J., Osman Andersen, T., ... Igel, C. (2019). Impact of device programming on the success of the first anti-tachycardia pacing therapy: An anonymized large-scale study. PLoS ONE, 14(8), [e0219533]. https://doi.org/10.1371/journal.pone.0219533

Vancouver

Shakibfar S, Krause O, Lund-Andersen C, Strycko F, Moll J, Osman Andersen T o.a. Impact of device programming on the success of the first anti-tachycardia pacing therapy: An anonymized large-scale study. PLoS ONE. 2019;14(8). e0219533. https://doi.org/10.1371/journal.pone.0219533

Author

Shakibfar, Saeed ; Krause, Oswin ; Lund-Andersen, Casper ; Strycko, Filip ; Moll, Jonas ; Osman Andersen, Tariq ; Høgh Petersen, Helen ; Hastrup Svendsen, Jesper ; Igel, Christian. / Impact of device programming on the success of the first anti-tachycardia pacing therapy : An anonymized large-scale study. I: PLoS ONE. 2019 ; Bind 14, Nr. 8.

Bibtex

@article{cd16572e69f743dabf611ddb78104df5,
title = "Impact of device programming on the success of the first anti-tachycardia pacing therapy: An anonymized large-scale study",
abstract = "BACKGROUND: Antitachycardia pacing (ATP) is an effective treatment for ventricular tachycardia (VT). We evaluated the efficacy of different ATP programs based on a large remote monitoring data set from patients with implantable cardioverter-defibrillators (ICDs).METHODS: A dataset from 18,679 ICD patients was used to evaluate the first delivered ATP treatment. We considered all device programs that were used for at least 50 patients, leaving us with 7 different programs and a total of 32,045 episodes. We used the two-proportions z-test (α = 0.01) to compare the probability of success and the probability for acceleration in each group with the corresponding values of the default setting.RESULTS: Overall, the first ATP treatment terminated in 78.4{\%}-97.5{\%} of episodes with slow VT and 81.5{\%}-91.1{\%} of episodes with fast VT. The default setting of the ATP programs with the number of sequences S = 3 was applied to treat 30.1{\%} of the slow and 36.6{\%} of the fast episodes. Reducing the maximum number of sequences to S = 2 decreased the success rate for slow VT (P < 0.0001, h = 0.38), while the setting S = 4 resulted in the highest success rate of 97.5{\%} (P < 0.0001, h = 0.27).CONCLUSION: While the default programs performed well, we found that increasing the number of sequences from 3 to 4 was a promising option to improve the overall ATP performance.",
author = "Saeed Shakibfar and Oswin Krause and Casper Lund-Andersen and Filip Strycko and Jonas Moll and {Osman Andersen}, Tariq and {H{\o}gh Petersen}, Helen and {Hastrup Svendsen}, Jesper and Christian Igel",
year = "2019",
doi = "10.1371/journal.pone.0219533",
language = "English",
volume = "14",
journal = "P L o S One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "8",

}

RIS

TY - JOUR

T1 - Impact of device programming on the success of the first anti-tachycardia pacing therapy

T2 - An anonymized large-scale study

AU - Shakibfar, Saeed

AU - Krause, Oswin

AU - Lund-Andersen, Casper

AU - Strycko, Filip

AU - Moll, Jonas

AU - Osman Andersen, Tariq

AU - Høgh Petersen, Helen

AU - Hastrup Svendsen, Jesper

AU - Igel, Christian

PY - 2019

Y1 - 2019

N2 - BACKGROUND: Antitachycardia pacing (ATP) is an effective treatment for ventricular tachycardia (VT). We evaluated the efficacy of different ATP programs based on a large remote monitoring data set from patients with implantable cardioverter-defibrillators (ICDs).METHODS: A dataset from 18,679 ICD patients was used to evaluate the first delivered ATP treatment. We considered all device programs that were used for at least 50 patients, leaving us with 7 different programs and a total of 32,045 episodes. We used the two-proportions z-test (α = 0.01) to compare the probability of success and the probability for acceleration in each group with the corresponding values of the default setting.RESULTS: Overall, the first ATP treatment terminated in 78.4%-97.5% of episodes with slow VT and 81.5%-91.1% of episodes with fast VT. The default setting of the ATP programs with the number of sequences S = 3 was applied to treat 30.1% of the slow and 36.6% of the fast episodes. Reducing the maximum number of sequences to S = 2 decreased the success rate for slow VT (P < 0.0001, h = 0.38), while the setting S = 4 resulted in the highest success rate of 97.5% (P < 0.0001, h = 0.27).CONCLUSION: While the default programs performed well, we found that increasing the number of sequences from 3 to 4 was a promising option to improve the overall ATP performance.

AB - BACKGROUND: Antitachycardia pacing (ATP) is an effective treatment for ventricular tachycardia (VT). We evaluated the efficacy of different ATP programs based on a large remote monitoring data set from patients with implantable cardioverter-defibrillators (ICDs).METHODS: A dataset from 18,679 ICD patients was used to evaluate the first delivered ATP treatment. We considered all device programs that were used for at least 50 patients, leaving us with 7 different programs and a total of 32,045 episodes. We used the two-proportions z-test (α = 0.01) to compare the probability of success and the probability for acceleration in each group with the corresponding values of the default setting.RESULTS: Overall, the first ATP treatment terminated in 78.4%-97.5% of episodes with slow VT and 81.5%-91.1% of episodes with fast VT. The default setting of the ATP programs with the number of sequences S = 3 was applied to treat 30.1% of the slow and 36.6% of the fast episodes. Reducing the maximum number of sequences to S = 2 decreased the success rate for slow VT (P < 0.0001, h = 0.38), while the setting S = 4 resulted in the highest success rate of 97.5% (P < 0.0001, h = 0.27).CONCLUSION: While the default programs performed well, we found that increasing the number of sequences from 3 to 4 was a promising option to improve the overall ATP performance.

U2 - 10.1371/journal.pone.0219533

DO - 10.1371/journal.pone.0219533

M3 - Journal article

C2 - 31393871

VL - 14

JO - P L o S One

JF - P L o S One

SN - 1932-6203

IS - 8

M1 - e0219533

ER -

ID: 225715075