The metabolic actions of neurotensin secreted from the gut

Research output: Contribution to journal › Review › Research › peer-review

Standard

The metabolic actions of neurotensin secreted from the gut. / Ratner, Cecilia; Johnsen, Cecilie Hundahl; Holst, Birgitte.

In: Cardiovascular Endocrinology, Vol. 5, No. 3, 09.2016, p. 102-111.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Ratner, C, Johnsen, CH & Holst, B 2016, 'The metabolic actions of neurotensin secreted from the gut', Cardiovascular Endocrinology, vol. 5, no. 3, pp. 102-111. https://doi.org/10.1097/XCE.0000000000000085

APA

Ratner, C., Johnsen, C. H., & Holst, B. (2016). The metabolic actions of neurotensin secreted from the gut. Cardiovascular Endocrinology, 5(3), 102-111. https://doi.org/10.1097/XCE.0000000000000085

Vancouver

Ratner C, Johnsen CH, Holst B. The metabolic actions of neurotensin secreted from the gut. Cardiovascular Endocrinology. 2016 Sep;5(3):102-111. https://doi.org/10.1097/XCE.0000000000000085

Author

Ratner, Cecilia ; Johnsen, Cecilie Hundahl ; Holst, Birgitte. / The metabolic actions of neurotensin secreted from the gut. In: Cardiovascular Endocrinology. 2016 ; Vol. 5, No. 3. pp. 102-111.

Bibtex

@article{e3b456f3a853404eb290091775ca8dcf,
title = "The metabolic actions of neurotensin secreted from the gut",
abstract = "Neurotensin (NT) is a 13 amino acid peptide hormone primarily expressed in the brain and in the gastrointestinal (GI) tract. NT in the brain is generally considered an anorexigenic neuropeptide, but the potential metabolic actions of GI tract NT have not been investigated extensively. In the GI tract, NT is mainly found in so-called N cells, but is also coexpressed with a number of functionally related hormones including glucagon-like peptide-1 (GLP-1) and peptide YY. NT, GLP-1, and peptide YY can further be released together in response to a number of different physiological stimuli and can coact on some but not all target organs. In line with the recent focus on developing antiobesity agents targeting more than one signaling pathway, NT may be a candidate for such polytherapy drugs in combination with other gut hormones such as GLP-1",
keywords = "coaction, glucagon-like peptide-1, metabolic regulation, neurotensin, peptide YY",
author = "Cecilia Ratner and Johnsen, {Cecilie Hundahl} and Birgitte Holst",
year = "2016",
month = sep,
doi = "10.1097/XCE.0000000000000085",
language = "English",
volume = "5",
pages = "102--111",
journal = "Cardiovascular Endocrinology",
issn = "2162-6898",
publisher = "Lippincott Williams & Wilkins",
number = "3",

}

RIS

TY - JOUR

T1 - The metabolic actions of neurotensin secreted from the gut

AU - Ratner, Cecilia

AU - Johnsen, Cecilie Hundahl

AU - Holst, Birgitte

PY - 2016/9

Y1 - 2016/9

N2 - Neurotensin (NT) is a 13 amino acid peptide hormone primarily expressed in the brain and in the gastrointestinal (GI) tract. NT in the brain is generally considered an anorexigenic neuropeptide, but the potential metabolic actions of GI tract NT have not been investigated extensively. In the GI tract, NT is mainly found in so-called N cells, but is also coexpressed with a number of functionally related hormones including glucagon-like peptide-1 (GLP-1) and peptide YY. NT, GLP-1, and peptide YY can further be released together in response to a number of different physiological stimuli and can coact on some but not all target organs. In line with the recent focus on developing antiobesity agents targeting more than one signaling pathway, NT may be a candidate for such polytherapy drugs in combination with other gut hormones such as GLP-1

AB - Neurotensin (NT) is a 13 amino acid peptide hormone primarily expressed in the brain and in the gastrointestinal (GI) tract. NT in the brain is generally considered an anorexigenic neuropeptide, but the potential metabolic actions of GI tract NT have not been investigated extensively. In the GI tract, NT is mainly found in so-called N cells, but is also coexpressed with a number of functionally related hormones including glucagon-like peptide-1 (GLP-1) and peptide YY. NT, GLP-1, and peptide YY can further be released together in response to a number of different physiological stimuli and can coact on some but not all target organs. In line with the recent focus on developing antiobesity agents targeting more than one signaling pathway, NT may be a candidate for such polytherapy drugs in combination with other gut hormones such as GLP-1

KW - coaction

KW - glucagon-like peptide-1

KW - metabolic regulation

KW - neurotensin

KW - peptide YY

U2 - 10.1097/XCE.0000000000000085

DO - 10.1097/XCE.0000000000000085

M3 - Review

VL - 5

SP - 102

EP - 111

JO - Cardiovascular Endocrinology

JF - Cardiovascular Endocrinology

SN - 2162-6898

IS - 3

ER -

ID: 170736638