Chlamydia and sudden infant death syndrome. A study of 166 SIDS and 30 control cases
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Chlamydia and sudden infant death syndrome. A study of 166 SIDS and 30 control cases. / Banner, Jytte; Lundemose, A G; Gregersen, M; Helweg-Larsen, K; Simonsen, J.
In: International Journal of Legal Medicine (Print), Vol. 104, No. 1, 12.1990, p. 3-7.Research output: Contribution to journal › Journal article › Research › peer-review
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T1 - Chlamydia and sudden infant death syndrome. A study of 166 SIDS and 30 control cases
AU - Banner, Jytte
AU - Lundemose, A G
AU - Gregersen, M
AU - Helweg-Larsen, K
AU - Simonsen, J
PY - 1990/12
Y1 - 1990/12
N2 - Chlamydia inclusions could be demonstrated by an immunofluorescence assay in formalin-fixed lung sections in 32 of 166 cases (19.4%) of Sudden Infant Death Syndrome (SIDS) and in the lungs of only 1 of 30 infants with a known cause of death (3.3%). The difference is statistically significant (P = 0.04). Chlamydia trachomatis is an agent of pneumonia in 1-4 month-old infants who have acquired the disease from an infected cervix during birth, but other chlamydia species are also capable of causing pneumonia. The lung sections of the 32 chlamydia positive SIDS cases did not show typical histological signs of pneumonia. Even though chlamydia inclusions were detected in the lungs of 32 SIDS cases a causal relation between chlamydia infection and SIDS could not be demonstrated.
AB - Chlamydia inclusions could be demonstrated by an immunofluorescence assay in formalin-fixed lung sections in 32 of 166 cases (19.4%) of Sudden Infant Death Syndrome (SIDS) and in the lungs of only 1 of 30 infants with a known cause of death (3.3%). The difference is statistically significant (P = 0.04). Chlamydia trachomatis is an agent of pneumonia in 1-4 month-old infants who have acquired the disease from an infected cervix during birth, but other chlamydia species are also capable of causing pneumonia. The lung sections of the 32 chlamydia positive SIDS cases did not show typical histological signs of pneumonia. Even though chlamydia inclusions were detected in the lungs of 32 SIDS cases a causal relation between chlamydia infection and SIDS could not be demonstrated.
KW - Age Distribution
KW - Case-Control Studies
KW - Chlamydia Infections
KW - Denmark
KW - Female
KW - Fluorescent Antibody Technique
KW - Humans
KW - Infant
KW - Infant, Newborn
KW - Infectious Disease Transmission, Vertical
KW - Lung
KW - Pregnancy
KW - Pregnancy Complications, Infectious
KW - Prospective Studies
KW - Retrospective Studies
KW - Sudden Infant Death
M3 - Journal article
C2 - 11453089
VL - 104
SP - 3
EP - 7
JO - International Journal of Legal Medicine
JF - International Journal of Legal Medicine
SN - 0937-9827
IS - 1
ER -
ID: 46809494